AACR Project Genie


AACR PROJECT GENIE and the National Leiomyosarcoma Foundation in Collaborative Advocacy/Support

The AACR Project GENIE initiative is recognized by the National Leiomyosarcoma Foundation (NLMSF) as a valuable tool in cancer genomics with a mission of advancing the field of precision oncology.  This program is instrumental in improving the field of precision oncology through the development of a global registry of genomic and clinical information from cancer patients around the world.  The genomic data obtained from tumors sequenced from thousands of cancer patients and linked to their clinical care information will enable researchers and clinicians to study the natural history of tumors, gene mutations, and their associations with patient outcomes.

AACR Project GENIE: Data

The first set of cancer genomic data aggregated through AACR Project Genomics Evidence Neoplasia Information Exchange (GENIE) was available to the global community in January 2017.  The second data set was released in January 2018 adding more than 7,500 records to the database. The combined dataset now includes more than 39,000 de-identified genomic records collected from patients who were treated at each of the consortium’s participating institutions, making it among the largest fully public cancer genomic datasets released to date.  These data will be continuously updated on a quarterly basis.
The combined dataset now includes data for over 60 major cancer types, including data from greater than 6,000 patients with lung cancer, nearly 4,500 patients with breast cancer, and more than 4,300 patients with colorectal cancer.
For more details about the data, and how to use it, consult the data guide.

NLMSF’s support of this groundbreaking program is critical at this time for the Leiomyosarcoma patient community.  By supporting and collaborating with the AACR Project GENIE, we can together shine a light on the role of rare mutations in the development of cancer and responsiveness to treatment regimens, therefore changing the future of molecular oncology for the Leiomyosarcoma patient community.

The NLMSF is proud to support the AACR Project GENIE in its focus to impact research on a global scale.  AACR Project GENIE’s database will allow researchers from around the world to investigate the link between genetics and clinical data, including treatment decisions, to improve clinical decision making and enhance outcomes for patients with all types of cancer, including Leiomyosarcoma.  Together we can make a difference!

Here is an overview of Project GENIE from AACR.

Read more here: AACR project GENIE: The Sharing Economy Comes To the Clinic

Founding Consortium Participants